ACCELA webinar recording : IntraVital Microscopy (IVM): In Vivo Live Cell Imaging Platform

During the last decade, the intravital microscopy has become a highly valuable, indispensable technique in wide areas of biomedical sciences such as immunology, neuroscience, developmental and tumor biology. In vivo visualizations of gene expression, protein activity, cell trafficking, cell-cell / cell-microenvironment interactions and various physiological responses to external stimuli have been achieved. Additionally, it’s a unique tool in the development of new therapeutics and diagnostics by providing improved accuracy and reliability in in vivo target validation with delivery monitoring and efficacy assessment. It has been used to directly analyze the delivery and efficacy of new biopharmaceuticals such as antibodies, cell therapy, gene therapy, nucleic acids and exosome in an in vivo microenvironment.

In this talk, a real-time laser-scanning intravital confocal/two-photon microscopy system will be introduced. The imaging system has been extensively optimized for in vivo cellular-level imaging of internal organs in live animal model for various human diseases, which can acquire a real-time multi-color fluorescence microscopic image in sub-micron resolution. Intravital microscopic imaging of various organs including skin, liver, spleen, pancreas, kidney, small intestine, colon, retina, lung, heart, lymph node, and bone marrow will be briefly introduced.

Tuesday, June 29th, 11:00 CET
Dr. Pilhan Kim, Korea Advanced Institute of Science and Technology (KAIST)
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