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Theranostics: From Mice to Men and Back

MOLECUBES

Jun 25, 2024

Recorded webinar
Presenters: Prof. Dr. Ken Herrmann and Prof. Dr. Katharina Lückerath – Moderator: Hannah Notebaert

Orion 2024 AACR poster: 17-plex single-step stain and imaging of cell Lung Carcinoma

RareCyte

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RareCyte Orion is a benchtop, high resolution, whole slide multimodal imaging instrument. A combination of quantitative...

Hypoxia in the Tumor Immune Microenvironment (TIME)

Bruker Biospin

Jun 6, 2024

Thursday, 11 July 2024, 16:00 CET | 10:00 EST
Zaver M. Bhujwalla, PhD...

X-RAD 320 for irradiation therapy during quantifying study for in vivo collagen reorganization

Precision X-Ray

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Quantifying in vivo collagen reorganization during immunotherapy in murine melanoma with second harmonic generation...

Jul 3, 2024

Use of MRI and microCT to evaluate gene therapy for the treatment of discogenic back pain

Bruker Biospin

Jun 4, 2024

MRI images were obtained using the 9.4T Bruker BioSpec system, equipped with 40 mm 1H quadrature volume resonator, and...

Exosome-Mediated Delivery of Small Molecules, RNA & DNA for Development of Novel Cancer Therapeutics

Spectral Instruments Imaging

Jun 3, 2024

Disha Moholkar of University of Louisville's Gupta Lab
Tuesday, June 11, 2024, 6:30 PM
...

Emulate in vivo conditions – introduce shear flow to your experiments with BioFlux system

Cell Microsystems

May 27, 2024

Most research is still conducted in vitro without the presence of flow. We use the BioFlux System to give you the...

Jul 3, 2024

High-frequency Ultrasound System For Preclinical Imaging

S-Sharp

May 13, 2024

The Prospect T1 is an innovative high-frequency ultrasound system designed specifically for in vivo preclinical imaging...

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Column-Free CD14+ Monocyte Isolation using 50nm Superparamagentic Beads on MARS® Bar

Apr 25, 2024

Professional antigen-presenting cells, dendritic cells are essential for controlling immune responses. Numerous clinical trials have employed dendritic cells as both medications and vaccines for the treatment of cancer. As crucial innate immune cells, macrophages can mediate the phagocytosis of hazardous cells or materials and take part in efficient tissue regeneration when they become activated. Therefore, cell-based therapeutics using ex vivo-generated macrophages have been tested in clinical settings. Peripheral blood monocytes can be used to produce dendritic cells and macrophages. In order to facilitate reliable, repeatable, and streamlined monocyte isolation processes, new products and technologies are required.
50 nm superparamagnetic particles have a larger surface area than conventional micron-sized beads, which are known to have low efficiency and require a de-beads procedure before being used in downstream applications. Clinical applications have made use of 50nm magnetic beads that are commercially accessible. For effective separation, though, columns must be utilized with the 50 nm magnetic beads that are currently on the market. Here, we demonstrate the isolation of CD14+ monocytes on a closed, automated system MARS® Bar utilizing Applied Cells IngenuityTM 50 nm beads and our unique column-free technique.

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Related technologies: Cell separation & Enrichment

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Applied Cells

Revolutionary solution to complete the workflow of cell separation and enrichment products, which increase cell separation efficiently by fundamentally changing how physics is employed in the process.

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