Accelerate to discover

Back to filter

Related topics

Theranostics: From Mice to Men and Back

MOLECUBES

Jun 25, 2024

Recorded webinar
Presenters: Prof. Dr. Ken Herrmann and Prof. Dr. Katharina Lückerath – Moderator: Hannah Notebaert

Orion 2024 AACR poster: 17-plex single-step stain and imaging of cell Lung Carcinoma

RareCyte

Jun 21, 2024

RareCyte Orion is a benchtop, high resolution, whole slide multimodal imaging instrument. A combination of quantitative...

Hypoxia in the Tumor Immune Microenvironment (TIME)

Bruker Biospin

Jun 6, 2024

Thursday, 11 July 2024, 16:00 CET | 10:00 EST
Zaver M. Bhujwalla, PhD...

X-RAD 320 for irradiation therapy during quantifying study for in vivo collagen reorganization

Precision X-Ray

Jun 5, 2024

Quantifying in vivo collagen reorganization during immunotherapy in murine melanoma with second harmonic generation...

Jul 3, 2024

Use of MRI and microCT to evaluate gene therapy for the treatment of discogenic back pain

Bruker Biospin

Jun 4, 2024

MRI images were obtained using the 9.4T Bruker BioSpec system, equipped with 40 mm 1H quadrature volume resonator, and...

Exosome-Mediated Delivery of Small Molecules, RNA & DNA for Development of Novel Cancer Therapeutics

Spectral Instruments Imaging

Jun 3, 2024

Disha Moholkar of University of Louisville's Gupta Lab
Tuesday, June 11, 2024, 6:30 PM
...

Emulate in vivo conditions – introduce shear flow to your experiments with BioFlux system

Cell Microsystems

May 27, 2024

Most research is still conducted in vitro without the presence of flow. We use the BioFlux System to give you the...

Jul 3, 2024

High-frequency Ultrasound System For Preclinical Imaging

S-Sharp

May 13, 2024

The Prospect T1 is an innovative high-frequency ultrasound system designed specifically for in vivo preclinical imaging...

Show all topics (10)

Small animal 13C-hyperpolarized MRI

Feb 8, 2019

Polarization of agents has been performed using dynamic nuclear polarization (DNP) and parahydrogen induced polarization (PHIP) methods, and imaging has been performed using both dedicated preclinical scanners at fields up to 14 Tesla(T) or clinical scanners. Polarization techniques differ in the range of probes that can be produced and the performance of the resulting product for imaging. Additionally, in part because the lifetime of a hyperpolarized probe is shortened relative to the field of the scanner used, there is a growing trend for preclinical laboratories focused in 13C-H MRI studies to employ relatively small and low field magnets like the Bruker BioSpec 3T, a compact preclinical imaging system that has no need for liquid cryogen filling. In case of the BioSpec 3T, the translational field strength of 3 Tesla further fosters possible translations to clinical 3 Tesla systems and offers the advantage of much stronger gradients to accelerate the image readout. An overview of current and emerging preclinical scanner technology, polarization technologies, and biological applications relevant to 13C-HP-MRI is provided here.

Do you want to learn more, just read the whole article!

Scientific paper
Application

Related technologies: X-ray and micro computed tomography

Get more info

Miroslav Vecheta

Support specialist

Miroslav

Vecheta

+420 210 323 421

Send Message

Brand profile

Bruker Biospin

Bruker is a performace leader in preclinical imaging instrumentation. Bruker offers nine imaging modalities: PET, SPECT, CT, MRI, MPI, fluorescence, luminiscence, radioisotipic imaging and X-ray.

Related products

Albira combines PET, SPECT and CT imaging in a unique and extremely powerful way

show detail

The world’s fastest, low-dose, high-resolution micro-CT

show detail

The high performance, stand-alone, fast, desk-top in vivo micro-CT

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey