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“The xCELLigence system proved to be a unique and invaluable technology in the development of new therapeutics for the steroid hormone sensitive cancers. It enabled us to analyze detailed proliferation dynamics of various cancer cell types, in response to manipulation of complex signaling network by steroid hormone receptors and enzymes involved in the steroid hormone biosyntesis.”

Dr. David Sedlák

Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic

Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic

“xCELLigence system helped my research in performing real-time evaluation of the toxicological profile for several types of innovative drugs that were tested on both primary cells and standard cell lines. Additionally, this platform demonstrated high sensitivity of detection of intracellular signaling events for drugs targeting protein kinases-mediated cellular pathways.”

Dr. Monica Neagu

‘Victor Babeș’ National Institute of Pathology, Bucharest, Romania

‘Victor Babeș’ National Institute of Pathology, Bucharest, Romania

„Our researches are mostly focused in the context of type II Diabetes, Obesity and a broad range of applications in cell biolabeling, cancer treatment, metastasis and therapeutic drug monitoring. Compared to traditonal end-point method, xCelligence system revolutionized our workflow adding real-time monitoring of cells inside incubator as an fundamental factor to assess long term effect of different compounds of interest.”

Dr Marta Kepinska

Wroclaw Medical University, Poland

Wroclaw Medical University, Poland

“We were delighted to use xCelligence DP in the research on the proliferation of bacterial strains in relation to antibiotic resistance and pathogenicity. The number of data collected during experiments extended these obtained by any other technique used in analysis ow grow curve. We also appreciate the fact that software provides an accessibly and convenient format of data to the statistical analysis. The result of the study will be presented at the conference: 5th International Caparica Conference in Antibiotic Resistance 2022, Portugal. We hope that xCelligence DP will permanently contribute our study soon.”

Dr Tomasz Jarzembowski

Medical University of Gdańsk, Poland

Medical University of Gdańsk, Poland

“The xCELLigence RTCA SP analysis is without any doubts a proven non-invasive and sensitive method for monitoring the viability, proliferation or migration of cells in real time and thus complements and explains a number of end-point experiments. Our laboratory deals with the study of new natural molecules or compounds prepared semisynthetically. The analysis software is also intuitive and complete, moreover, ACCELA as a local supplier is able to provide qualified training and service.”

Dr Darja Koutová

Charles University, Faculty of Medicine in Hradec Kralove, Czech Republic

Charles University, Faculty of Medicine in Hradec Kralove, Czech Republic

xCELLigence DP – Agilent technologies

The technology extended into most powerful cell migration tool

The RTCA DP Analyzer has three integrated stations for E-Plates 16 or CIM-Plates 16.It is located inside a tissue culture incubator. Each of the three 16-well plate holders can be used independently under the RTCA Software. The RTCA DP Analyzer can automatically select wells for measurement and continuously transfer measured impedance data to the computer. Cell Index values, derived from the measured impedances, are continuously displayed on the Software user interface.

The RTCA DP Instrument is composed of three main components: 

  • RTCA DP Analyzer
  • RTCA Control Unit
  • E-Plate 16 or CIM-Plates 16

RTCA DP Instrument Highlights: 

  • Highly flexible low throughput: Accommodates up to three E-Plates 16 or CIM-Plates 16 simultaneously
  • Flexibility: Independent operation of the three 16 well plates by up to three different users
  • Clear data presentation: 16-well graph shows individual Cell Index curves for all 16 wells
  • Broad range of applications for cellular assays and cell invasion migration assays

More info at: https://www.aceabio.com/products/rtca-dp/

Riccardo Pasculli

Head of application support

Riccardo Pasculli

+420 731 127 717

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