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"xCELLigence system helped my research in performing real-time evaluation of the toxicological profile for several types of innovative drugs that were tested on both primary cells and standard cell lines. Additionally, this platform demonstrated high sensitivity of detection of intracellular signaling events for drugs targeting protein kinases-mediated cellular pathways."

Dr. Monica Neagu

'Victor Babeș' National Institute of Pathology, Bucharest, Romania

The xCELLigence system proved to be a unique and invaluable technology in the development of new therapeutics for the steroid hormone sensitive cancers. It enabled us to analyze detailed proliferation dynamics of various cancer cell types, in response to manipulation of complex signaling network by steroid hormone receptors and enzymes involved in the steroid hormone biosyntesis."

Dr. David Sedlák

Institute of Molecular Genetics of the ASCR, Prague, Czech Republic

“I used the xCELLigence DP system to study the effectiveness of CAR-T against target cancer cells. I was able to observe the effectiveness of cell therapy during the entire experiment with great accuracy. Both devices and software are easy and pleasant to use”

Dr Anna Bujak, Principal Research Scientist

Helix Immuno-Oncology, Warsaw, Poland

"The xCELLigence RTCA SP analysis is without any doubts a proven non-invasive and sensitive method for monitoring the viability, proliferation or migration of cells in real time and thus complements and explains a number of end-point experiments. Our laboratory deals with the study of new natural molecules or compounds prepared semisynthetically. The analysis software is also intuitive and complete, moreover, ACCELA as a local supplier is able to provide qualified training and service."

Dr Darja Koutová

Charles University, Faculty of Medicine in Hradec Kralove, Czech Republic

The xCELLigence RTCA DP system is an easy to use platform with intuitive software and a variety of online tutorials for beginners and experience users. It is great tool for our cell therapies development, our laboratory obtained exciting results for cytotoxicity assays using adherent and suspension cells.

 

Dr Mirabela Cristea

Center for gene and cellular therapies in the treatment of cancer (OncoGen), Timisoara, Romania 

xCELLigence MP - Agilent technologies

Higher throughput for xCELLigence cell based assay

The RTCA MP Station is located inside a tissue culture incubator and is capable of switching any one of the wells on any of six E-Plates to the RTCA Analyzer for impedance measurement.Each of the six E-Plate holders can be used independently under the RTCA Software. The RTCA Analyzer can automatically select wells for measurement and continuously transfer measured impedance data to the computer. Cell Index values, derived from the measured impedances, are continuously displayed on the Software user interface.

The RTCA MP Instrument is composed of four main components: 

  • RTCA Analyzer
  • RTCA MP Station
  • RTCA Control Unit
  • E-Plate 96

RTCA MP Instrument Highlights:

  • Higher assay throughput: Accommodates up to six E-Plates simultaneously
  • Flexibility: Independent operation of six E-Plates by up to six different users
  • Easy to use: Motorized mechanism for E-Plate engagement onto RTCA MP Station
  • Clear data presentation: 96-well graph shows individual Cell Index curves for all 96 wells

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https://www.aceabio.com/products/rtca-mp/

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Cancer Immunotherapy Applications of xCELLigence Real-Time Cell Analysis (RTCA) Systems xCELLigence cancer immunotherapy: NK cell-mediated cytolysis In vitro hypoxia studies using xCELLigence platform Real-time chemotaxis of macrophages Quantifying virus-mediated cytopathic effect with xCELLigence platform Introducing the xCELLigence Immunotherapy kit – B Cell killing assay Real-time monitoring of Human Skin-Derived Precursor (SKPs) cell differentiation Assessment of CAR T Cell killing capacity against solid tumors-Thursday, October 20, 2016, 5 pm CEST Cancer immunotherapy: Macrophage-mediated phagocytosis Monitoring in real time the formation and removal of biofilms from clinical related pathogens xCELLigence in personalized cancer medicine Investigating the hallmarks of cancer using xCELLigence system Monitoring the formation and removal of biofilms from clinically relevant pathogens in real-time Real-time determination of virus titers using cell electric impedance technology Label-free monitoring of T cell activation by the impedance-based system A novel high throughput assay for diagnosis by real-time monitoring of parasite motility Optimization of (CAR) T cell design guided by sensitive sssessment of B cell killing Cellular impedance measurement- novel method for in-vitro investigation of drug efficacy Cellular impedance measurement- response of OVCAR-3 cells to Cisplatin and hyperthermia ACEA webinar series: Using xCELLigence RTCA to study biofilms formation Kinase study of cytotoxicity voted paper of the year. ACEA Biosciences launch xCELLigence RTCA software Pro for immunotherapy applications New technique for dynamic monitoring of liquid tumor Cytotoxicity xCELLigence system: rapid and sensitive, ideal for infectious viral assays.
Riccardo Pasculli

Head of application support

Riccardo

Pasculli

+420 731 127 717

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