Accelerate to discover
Technologies
Type of the news
Brands
Optical Imaging with Cherenkov Luminescence Inform PET and SPECT Study Design
Cherenkov Luminescence Imaging (CLI) can enhance PET and SPECT studies by enabling rapid, cost-effective assessment of radiotracer biodistribution, protocol optimization, and early-stage evaluation before nuclear imaging.
2026-09-21
Intravital imaging reveals the early astrocytic response to ischemic stroke
IVIM-C enabled longitudinal, real-time imaging of living brain tissue, revealing the rapid H₂O₂ surge in astrocytes and its relationship to vascular disruption and glial barrier formation.
2026-09-14
A combination of systemic nanoparticles for caveolae-mediated gene delivery to the brain
This study shows that systemic mannitol induces caveolae in the brain endothelium. Mannitol-modified nanoparticles exploit this to cross the BBB, enhancing gene delivery.
2026-05-20
Cutaneous T cell lymphoma atlas reveals malignant TH2 cells supported by a B cell-rich tumor microen
The study provides a high-resolution atlas of cutaneous T cell lymphoma, identifying that malignant cells resemble TH2 cells. It highlights how a B cell-rich microenvironment supports tumor growth, offering new targets for therapy.
2026-05-04
Comprehensive analysis of B cell repopulation in ocrelizumab-treated patients with MS
Using the Curiox Pluto platform to automate immune profiling, ocrelizumab’s effects in MS reveal repopulation of transitional naïve B cells at 6 months and linked shifts in T/myeloid markers and plasma proteins.
2026-04-07
Accelerating Antibody Discovery with the WOLF G2 Cell Sorter
Site-directed antibodies targeting driver mutations of the KRAS protein
2026-03-16
More protein in less time: Automated native membrane protein purification with CyBio FeliX
Automated membrane protein purification with CyBio FeliX and NativeMP reduces processing time to under three hours while preserving protein integrity and ensuring high reproducibility.
2026-06-29
Combined Denoising and Resolution Enhancement Algorithms for Intravital Two-Photon Imaging
The study compared several image processing techniques, finding that the enhanced Super-Resolution Radial Fluctuations (eSRRF) combined with a trained denoising model significantly improved spatial resolution and mitochondrial structure visualization compared to other algorithms. Algorithms Evaluated: The study tested Gaussian and median filtering against a trained denoising model, followed by resolution enhancement using either eSRRF or […]
2026-05-14
High-Throughput UVA-Based Thermal Shift Assays for Hydrophobic Proteins Using the qTOWER iris
This note demonstrates a UVA-based Thermal Shift Assay on the qTOWER iris, enabling sensitive detection of protein stability and expanding qPCR use to protein analysis.
2026-04-23
Microscopy-guided subcellular proteomic discovery by high-speed ultra-content photo-biotinylation
Syncell developed a method combining microscopy, photo-biotinylation, and mass spectrometry, enabling high-resolution mapping of proteins in subcellular regions, accelerating discoveries in spatial proteomics research.
2026-03-23
NEW: TIDeX – Total Ionizing Dose Instrument
The all-in-one X-ray platform designed to streamline Total Ionizing Dose (TID) effect testing with accuracy, control, and repeatability
2026-03-12
mRNA vaccine immunity is enhanced by hepatocyte detargeting and not dependent on dendritic cell expression
mRNA vaccine efficacy is enhanced by preventing expression in hepatocytes rather than promoting it in dendritic cells. The findings highlight tissue-specific targeting as a potential strategy for improving vaccines and cancer immunotherapies.
2026-06-05
Efficient DNA purification from cells: Automated workflows with sbeadex Lightning and CyBio FeliX
This application note presents a rapid, automated DNA purification workflow using the CyBio FeliX system with sbeadex Lightning technology, enabling high-quality results in just minutes while reducing hands-on time and increasing throughput.
2026-05-06
PHF19 drives the formation of PRC2 clusters to enhance motility in TNBC cells
Polycomb repressive complex 2 (PRC2) is a key regulator of transcriptional repression and chromatin organization, essential in development and disease. While its enzymatic activity is well characterized, the factors governing PRC2 subnuclear organization, particularly in cancer cells, are largely unknown. Here, the researchers integrate in situ subcellular proteomics, high-resolution imaging, and functional genomics to investigate […]
2026-04-14
Harnessing the Nanoflow cytometer Exoplorer to characterize surface proteins of Exosomes
miR-185-5p Derived From hUC-MSC Exosomes via Suspension Culture Under Hypoxic Conditions Promotes Scarless Wound Healing in Mice by Precisely Regulating Collagen I/III Regeneration
2026-03-19
BioFocus newsletter
Register to receive Brand new technology development, Important product updates, Interesting scientific events and more!
Technologies