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Measure EV Purity Results by Calculating the Membrane Ratio with the Exoplorer
Working with Extracellular Vesicles (EVs)? Imagine being able to effortlessly measure EV quality. This is possible with the Exoplorer™ Nano-flow Cytometer — a highly effective tool for nanoparticle-level analysis.
2025-10-20
Image-activated cell sorting
The NanoCellect VERLO Image-Guided Cell Sorter is mentioned in the attached Nature Reviews Bioengineering paper (Ding et al., 2025) reviewing commercially available Image-Activated Cell Sorting systems.
2025-09-16
Monitoring mRNA vaccine antigen expression in vivo using PET/CT
The aim of this study was to evaluate the ability of PET/CT imaging to track mRNA vaccine antigen expression in mammalian systems. The researchers used eDHFR as a PET reporter gene, fused to the SARS-CoV-2 spike protein.
2025-09-08
Control of behavioral uncertainty by divergent frontal circuits
Preprint on bioRxiv shows that plasma p-tau181, NfL, and GFAP effectively differentiate Alzheimer’s from FTD and DLB, while Aβ₁₋₄₂/₁₋₄₀ adds little diagnostic value.
2025-06-04
Protocol for simultaneous isolation of high-quality & high-quantity cardiomyocytes and non-myocytes
A protocol to simultaneously isolate high-quality and high-quantity cardiomyocytes and non-myocyte cells, including immune cells, from adult rat hearts. Detailed procedures for viability analysis and cell type identification using Wolf sorter.
2025-03-28
Optimizing Substrate Dosing for Reliable Bioluminescence Imaging (BLI)
Best Practices for Substrate Dosing: dose based on weight, prepare fresh solutions, use standardized routes of administration and more
2025-03-17
Subcutaneous delivery of MSC induces immunoregulatory effects in the lymph node
Mice were imaged under anaesthesia (2.5% isoflurane in oxygen), daily until the bioluminescence signal disappeared. Imaging was performed in an Ami-HTX Small Animal Imager and analysed with Aura Imaging Software, from Spectral Instruments Imaging.
2025-09-12
Incorporation of SARS-CoV-2 spike NTD to RBD protein vaccine improves immunity against viral variant
By fusing the spike protein's terminal domain (NTD) with its receptor-binding domain (RBD), researchers have engineered a protein vaccine that significantly amplifies both T-cell responses and antibody breadth.
2025-06-25
Curious how PET imaging and reporter gene tracking are transforming CAR-T cell therapy in oncology?
Recorded webinar is recommended if you are working or you are interested by translational studies in oncology, immune therapy, and biomedical imaging.
2025-06-02
Age-associated B cells are heterogeneous and dynamic drivers of autoimmunity in mice.
Here we report, in the MRL/lpr SLE model, unexpected heterogeneity among ABC-like cells for expression of the integrins CD11b and CD11c, T-bet, and memory or plasmablast markers.
2025-03-21
Francisella tularensis induces Th1 like MAIT cells conferring protection against infection
F. tularensis LVS activates MAIT reporter cells in vitro in an MR1-dependent manner and induces a systemic MAIT cell response in vivo.
2025-02-27
Pericytes promote metastasis by regulating tumor local vascular tone and hemodynamics
The anesthetized mouse was placed on a customized stage for tumor immobilization and colon tumor was exposed to intravital microscopy (IVM-MS2, IVIM Technology, Korea) equipped with 25× water immersion objective.
2025-09-10
Growing Mature Biofilms for Antimicrobial Screening, Host-pathogen Interactions, and Adhesion
We present the BioFlux shear flow system, a microfluidic flow cell array that enables the growth of biofilms in precisely controlled conditions, including shear stress, temperature, and environmental gas.
2025-06-18
High-throughput, physiological assays of leukocyte adhesion and rolling
BioFlux shear flow systems enable the visualization and analysis of all of the steps of the leukocyte adhesion cascade under physiological/pathological shear flow using one system.
2025-04-04
A comprehensive comparison on clustering methods for multi-slide spatially resolved transcriptomics
This study evaluates clustering methods for multi-slide spatial transcriptomics (ST) data, analyzing preprocessing techniques like PASTE and Harmony to guide method selection.
2025-03-19
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Technologies