Accelerate to discover

Age-associated B cells are heterogeneous and dynamic drivers of autoimmunity in mice.

Here we report, in the MRL/lpr SLE model, unexpected heterogeneity among ABC-like cells for expression of the integrins CD11b and CD11c, T-bet, and memory or plasmablast markers.

2025-03-21

Application
Scientific paper

A comprehensive comparison on clustering methods for multi-slide spatially resolved transcriptomics

This study evaluates clustering methods for multi-slide spatial transcriptomics (ST) data, analyzing preprocessing techniques like PASTE and Harmony to guide method selection.

2025-03-19

Application
Scientific paper

Preclinical SPECT and PET: Joint EANM and ESMI procedure guideline 2024

The aim of this guideline is to provide recommendations for the implementation of an effective and efficient quality control (QC) program for SPECT and PET systems in a preclinical imaging lab. Published online: 15 July 2024

2025-02-06

Product news
Scientific paper

IVIM Technology-Integrated Motion Artifact Compensation

Guarantee for optimal result in wide-range of spatio-temporal tissue movement from slowly moving tissue (e.g. abdominal organs such as liver, kidney, spleen) to rapidly moving tissue (e.g. thoracic organs such as heat, lung)

2024-09-12

Scientific paper
Technical breakthrough

Discover the Celloger live-cell analyzers : miniaturized and powerful tools for every Biologist

Celloger live-cell analyzers, image and analyze your cells in real-time, inside your incubator. With its exceptional image quality and unmatched convenience, Celloger products empowers and simplify any live-cell assay.

2024-06-19

Scientific paper

High-frequency Ultrasound System For Preclinical Imaging

The Prospect T1 is an innovative high-frequency ultrasound system designed specifically for in vivo preclinical imaging in small animals such as mice and rats. This compact and cost-effective tablet-based system provides high-resolution images.

2024-05-13

Application
Product news
Scientific paper

Optimizing Substrate Dosing for Reliable Bioluminescence Imaging (BLI)

Best Practices for Substrate Dosing: dose based on weight, prepare fresh solutions, use standardized routes of administration and more

2025-03-17

Application
Scientific paper

Get your cells ready for NGS with tiples nanodispenser MANTIS

Generating high-quality cDNA libraries for efficient sequencing of T-cell receptor mRNA from single cells.

2025-01-06

Application
Scientific paper

Scaling Whole-Genome Sequencing to >50,000 single cells using cellenONE

cellenONE technology enabled the creation of tens of thousands of high-quality single-cell genomes, paving the way for widespread adoption in research and clinical settings

2024-07-16

Application
Scientific paper
Technical breakthrough

X-RAD 320 for irradiation therapy during quantifying study for in vivo collagen reorganization

Quantifying in vivo collagen reorganization during immunotherapy in murine melanoma with second harmonic generation imaging

2024-06-05

Application
Scientific paper

“Range+T “ for Tight Sizing of HMW Libraries

We decided to do a deep dive into Range+T to get a better handle the method, and to develop best practices for using Diagenode Megaruptor 3 and PippinHT or BluePippin.

2024-05-10

Application
Scientific paper

Francisella tularensis induces Th1 like MAIT cells conferring protection against infection

F. tularensis LVS activates MAIT reporter cells in vitro in an MR1-dependent manner and induces a systemic MAIT cell response in vivo.

2025-02-27

Application
Product news
Scientific paper
Technical breakthrough

Don’t waste your time for homogenization and get best results in neurscience with Singulator!

Single-nuclei sequencing (SNS) is a transformative approach for dissecting cellular diversity in complex tissues like the brain. Effective isolation of high-quality cells with intact nuclei is essential for the success of this technique.

2025-01-06

Application
Scientific paper

Theranostics: From Mice to Men and Back

Recorded webinar Presenters: Prof. Dr. Ken Herrmann and Prof. Dr. Katharina Lückerath – Moderator: Hannah Notebaert

2024-06-25

Scientific paper

Use of MRI and microCT to evaluate gene therapy for the treatment of discogenic back pain

MRI images were obtained using the 9.4T Bruker BioSpec system, equipped with 40 mm 1H quadrature volume resonator, and ParaVision 6.0.1 software. MicroCT imaging of mouse spines were obtained using the Bruker SkyScan 1276.

2024-06-04

Application
Scientific paper

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