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Optimizing Substrate Dosing for ReliableBioluminescence Imaging (BLI)
Bioluminescence imaging relies on precise D-luciferin administration, as dosing variability impacts signal intensity and data consistency. Standardizing substrate delivery is essential for reproducible and high-quality in vivo imaging results.
2025-09-18
Subcutaneous delivery of MSC induces immunoregulatory effects in the lymph node
Mice were imaged under anaesthesia (2.5% isoflurane in oxygen), daily until the bioluminescence signal disappeared. Imaging was performed in an Ami-HTX Small Animal Imager and analysed with Aura Imaging Software, from Spectral Instruments Imaging.
2025-09-12
Curious how PET imaging and reporter gene tracking are transforming CAR-T cell therapy in oncology?
Recorded webinar is recommended if you are working or you are interested by translational studies in oncology, immune therapy, and biomedical imaging.
2025-06-02
Optimizing Substrate Dosing for Reliable Bioluminescence Imaging (BLI)
Best Practices for Substrate Dosing: dose based on weight, prepare fresh solutions, use standardized routes of administration and more
2025-03-17
Development of Image-Based In Vitro/In Vivo Platform for Targeting CAFs
Date & Time: Feb 12, 2025 6 PM CET.
Speaker: Dr. Pengyu Huang, Head of In Vivo Pharmacology at Simcere Zaiming and Simnova Biotherapeutics
2025-02-12
IVIM Technology-Integrated Motion Artifact Compensation
Guarantee for optimal result in wide-range of spatio-temporal tissue movement from slowly moving tissue (e.g. abdominal organs such as liver, kidney, spleen) to rapidly moving tissue (e.g. thoracic organs such as heat, lung)
2024-09-12
Pericytes promote metastasis by regulating tumor local vascular tone and hemodynamics
The anesthetized mouse was placed on a customized stage for tumor immobilization and colon tumor was exposed to intravital microscopy (IVM-MS2, IVIM Technology, Korea) equipped with 25× water immersion objective.
2025-09-10
Come meet us at FELASA
The Federation of European Laboratory Animal Science Associations congress
2025-05-21
Bruker Lunch Symposium at EMIM 2025 on March 12th
Don't miss the Lunch Symposium on March 12th, at 12:45 PM, in Room LS 01, during EMIM 2025!
Our colleague Igor Valerian is available for meetings at Bruker's booth 001 at EMIM on March 12th, in Bilbao, Spain.
2025-03-06
Preclinical SPECT and PET: Joint EANM and ESMI procedure guideline 2024
The aim of this guideline is to provide recommendations for the implementation of an effective and efficient quality control (QC) program for SPECT and PET systems in a preclinical imaging lab. Published online: 15 July 2024
2025-02-06
Hypoxia assessment using simultaneous multiparametric PET/MRI
A presentation on simultaneous PET/MRI methods and challenges in the characterization of hypoxia-induced physiological differences between breast cancer subtypes.
2024-09-11
Monitoring mRNA vaccine antigen expression in vivo using PET/CT
The aim of this study was to evaluate the ability of PET/CT imaging to track mRNA vaccine antigen expression in mammalian systems. The researchers used eDHFR as a PET reporter gene, fused to the SARS-CoV-2 spike protein.
2025-09-08
High-Resolution Intravital In Vivo Imaging with AI-Powered Image Denoising
In this webinar, experts discuss cutting-edge advancements in microscopy imaging and denoising technologies.
2025-04-14
The New Future of Micro-CT and 3D X-Ray Microscopy
Session I
Thursday, February 27
09:00 CST / Chicago
12:00 BRT / São Paulo
16:00 CET / Berlin
Session II
Thursday, February 27
19:00 CST / Chicago
Friday, February 28
09:00 SGT / Singapore
10:00 JST / Tokyo
2025-02-12
Watch Aura 4.0 Instructional Tutorials – How To Acquire Data Using Easy Mode
Dr. Andrew Van Praagh explains how to acquire data using Easy Mode in Spectral Instruments Imaging's Aura software, version 4.0
2024-10-07
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