“Lago X is an exceptional tool for whole-body applications, with its exceptional reproducibility, signal stability and camera sensitivity, shortening imaging times to less then 1s. Based on our experience, we are able to detect metastases in cancer model much sooner and in more sites than other in-vivo systems. Lago X software is freely available for image processing and quantification, which allows involvement of broad research community into raw data analysis. Finally, we appreciate large field of view, which allows 10 adult mice to be imaged at once. Such features makes Lago X a breakthrough solution for high throughput and high demand in-vivo applications. “