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Optical Imaging with Cherenkov Luminescence Inform PET and SPECT Study Design
Cherenkov Luminescence Imaging (CLI) can enhance PET and SPECT studies by enabling rapid, cost-effective assessment of radiotracer biodistribution, protocol optimization, and early-stage evaluation before nuclear imaging.
2026-09-21
Biometra TAdvanced – Supported thermal cycler for 10x Genomics Single Cell and Spatial Applications
Perfect Partners to Unlock Cellular Insights. Understanding cell types and cell-cell interactions with major significance for health and disease.
2026-09-07
mRNA vaccine immunity is enhanced by hepatocyte detargeting and not dependent on dendritic cell expression
mRNA vaccine efficacy is enhanced by preventing expression in hepatocytes rather than promoting it in dendritic cells. The findings highlight tissue-specific targeting as a potential strategy for improving vaccines and cancer immunotherapies.
2026-06-05
PHF19 drives the formation of PRC2 clusters to enhance motility in TNBC cells
Polycomb repressive complex 2 (PRC2) is a key regulator of transcriptional repression and chromatin organization, essential in development and disease. While its enzymatic activity is well characterized, the factors governing PRC2 subnuclear organization, particularly in cancer cells, are largely unknown. Here, the researchers integrate in situ subcellular proteomics, high-resolution imaging, and functional genomics to investigate […]
2026-04-14
Accelerating Antibody Discovery with the WOLF G2 Cell Sorter
Site-directed antibodies targeting driver mutations of the KRAS protein
2026-03-16
Non-invasive real-time pulsed Doppler assessment of blood flow in mouse ophthalmic artery
Imaging was performed under isoflurane anesthesia using the SkyScan 1276 instrument with an X-ray source voltage and current of 70 kV and 200 μA and a 1 mm Aluminum filter. A total of 1200 projection images were acquired at resolution of 13μm.
2026-02-06
Integrated IP-MS and Optoproteomics Reveal Dynamic Remodeling of Protein Interaction Networks
Combining IP-MS with Syncell optoproteomics reveals how the NLRP3 inflammasome dynamically reorganizes its protein interaction network and identifies a novel regulatory mechanism.
2026-07-13
Efficient DNA purification from cells: Automated workflows with sbeadex Lightning and CyBio FeliX
This application note presents a rapid, automated DNA purification workflow using the CyBio FeliX system with sbeadex Lightning technology, enabling high-quality results in just minutes while reducing hands-on time and increasing throughput.
2026-05-06
Standardized Thawing and Sample Preparation of ARCTis Cryopreserved Human Tumor Cells
The standardized and automatic handling of cryopreserved biological samples plays an increasingly important role in today’s in vitro testing. This is due to the trend to develop more complex disease models to increase the data quality of studies.
2026-03-30
Harnessing the WOLF Cell Sorter for Cutting‑Edge Senescence Research
Senescent Endothelial Cells in Cerebral Microcirculation Are Key Drivers of Age-Related Blood–Brain Barrier Disruption, Microvascular Rarefaction, and Neurovascular Coupling Impairment in Mice
2026-02-18
Metabolomic fingerprints of PAH exposure – identifying toxicological biomarkers in dynamic culture
This study not only highlights the use of spheroids for mechanistic toxicological studies but also provides a framework for identifying potential metabolic biomarkers of PAH exposure. Use of ClinoStar for hepatic HepG2 spheroids made the difference !
2026-02-05
More protein in less time: Automated native membrane protein purification with CyBio FeliX
Automated membrane protein purification with CyBio FeliX and NativeMP reduces processing time to under three hours while preserving protein integrity and ensuring high reproducibility.
2026-06-29
High-Throughput UVA-Based Thermal Shift Assays for Hydrophobic Proteins Using the qTOWER iris
This note demonstrates a UVA-based Thermal Shift Assay on the qTOWER iris, enabling sensitive detection of protein stability and expanding qPCR use to protein analysis.
2026-04-23
Harnessing the Nanoflow cytometer Exoplorer to characterize surface proteins of Exosomes
miR-185-5p Derived From hUC-MSC Exosomes via Suspension Culture Under Hypoxic Conditions Promotes Scarless Wound Healing in Mice by Precisely Regulating Collagen I/III Regeneration
2026-03-19
Use of Vizgen’s MERSCOPE Platform to Uncover New Insights about Aging
Microglia activation orchestrates CXCL10-mediated CD8+ T cell recruitment to promote aging-related white matter degeneration - peer-reviewed paper outlines aging-related changes in white matter by single-cell and spatial transcriptomics
2026-02-11
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