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Harnessing the Nanoflow cytometer Exoplorer to characterize surface proteins of Exosomes
miR-185-5p Derived From hUC-MSC Exosomes via Suspension Culture Under Hypoxic Conditions Promotes Scarless Wound Healing in Mice by Precisely Regulating Collagen I/III Regeneration
2026-03-19
Accelerating Antibody Discovery with the WOLF G2 Cell Sorter
Site-directed antibodies targeting driver mutations of the KRAS protein
2026-03-16
Non-invasive real-time pulsed Doppler assessment of blood flow in mouse ophthalmic artery
Imaging was performed under isoflurane anesthesia using the SkyScan 1276 instrument with an X-ray source voltage and current of 70 kV and 200 μA and a 1 mm Aluminum filter. A total of 1200 projection images were acquired at resolution of 13μm.
2026-02-06
Direct delivery of plasmin using clot-anchoring thrombin-responsive nanoparticles
The targeted fibrinolytic efficacy of the plasmin-loaded CTNPs was then evaluated under flow using the Bioflux microfluidic device.
2026-01-28
The Path to Clinical Relevance: Moving from Spatial Transcriptomics to Protein Profiling
Spatial biology is a rapidly evolving discipline that advances human health by leveraging imaging technologies. It encompasses research activities ranging from whole-transcriptome profiling to clinically impactful single-protein biomarker tests.
2025-12-02
Perfusion: The Beating Heart of Single-Cell Biology and Cancer Immunotherapy
Single-cell biology has transformed our ability to uncover cellular diversity and dynamic behavior within complex tissues that are otherwise masked in population-level analyses.
2025-11-24
Harnessing the WOLF Cell Sorter for Cutting‑Edge Senescence Research
Senescent Endothelial Cells in Cerebral Microcirculation Are Key Drivers of Age-Related Blood–Brain Barrier Disruption, Microvascular Rarefaction, and Neurovascular Coupling Impairment in Mice
2026-02-18
Metabolomic fingerprints of PAH exposure – identifying toxicological biomarkers in dynamic culture
This study not only highlights the use of spheroids for mechanistic toxicological studies but also provides a framework for identifying potential metabolic biomarkers of PAH exposure. Use of ClinoStar for hepatic HepG2 spheroids made the difference !
2026-02-05
CXCL12+ fibroblastic reticular cells in lymph nodes facilitate immune tolerance
The popliteal LNs were exposed surgically and confocal intravital imaging was performed (IVM-CMS3). Twenty-five Z-stack images were obtained with a 3 μm axial interval. Time-lapse images were obtained at a 1-minute time interval for 20 minutes.
2026-01-26
Can you solve mouse CT imaging with 50um spatial resolution ?
MOLECUBES, a Bruker Company offers small footprint microCT for mice and rats, which meets most of your needs for in-vivo analysis and doesn't sacrifice the budget.
2025-10-22
Use of Vizgen’s MERSCOPE Platform to Uncover New Insights about Aging
Microglia activation orchestrates CXCL10-mediated CD8+ T cell recruitment to promote aging-related white matter degeneration - peer-reviewed paper outlines aging-related changes in white matter by single-cell and spatial transcriptomics
2026-02-11
Impact of aging on gene expression response to x-ray irradiation using mouse blood
Mice were restrained in a pie holder without anesthesia and they were either sham-irradiated or exposed to 4Gy x-rays of total body irradiation from an X-RAD 320 Biological Irradiator.
2026-02-02
Combination of low-energy X-ray & citric acid to inactivate E.coli, S.Typhimurium, L.Monocitogenes
Combined treatment with 0.5 kGy X-ray and 0.1 % CA significantly decreased biofilm cell counts by 5.10, 4.31, and 3.96 log CFU/coupon for E. coli O157:H7, S. Typhimurium, and L. Monocytogenes, respectively.
2025-12-03
Development of new albumin‑binding radiotracers for PET imaging of CSF
In this study by Peltoniemi et al., PET/CT imaging using the X-CUBE (CT) and ß-CUBE (PET) was used to non-invasively visualize cerebrospinal fluid (CSF) flow and glymphatic system dynamics in rats.
2025-11-28
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Technologies