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Combination of low-energy X-ray & citric acid to inactivate E.coli, S.Typhimurium, L.Monocitogenes
Combined treatment with 0.5 kGy X-ray and 0.1 % CA significantly decreased biofilm cell counts by 5.10, 4.31, and 3.96 log CFU/coupon for E. coli O157:H7, S. Typhimurium, and L. Monocytogenes, respectively.
2025-12-03
The Path to Clinical Relevance: Moving from Spatial Transcriptomics to Protein Profiling
Spatial biology is a rapidly evolving discipline that advances human health by leveraging imaging technologies. It encompasses research activities ranging from whole-transcriptome profiling to clinically impactful single-protein biomarker tests.
2025-12-02
Perfusion: The Beating Heart of Single-Cell Biology and Cancer Immunotherapy
Single-cell biology has transformed our ability to uncover cellular diversity and dynamic behavior within complex tissues that are otherwise masked in population-level analyses.
2025-11-24
Automated and efficient isolation of single cells into low volumes for scWGA
Single-cell whole-genome amplification (scWGA) is a powerful technique to massively amplify and analyse the genomes of individual cells.
2025-10-17
Subcutaneous delivery of MSC induces immunoregulatory effects in the lymph node
Mice were imaged under anaesthesia (2.5% isoflurane in oxygen), daily until the bioluminescence signal disappeared. Imaging was performed in an Ami-HTX Small Animal Imager and analysed with Aura Imaging Software, from Spectral Instruments Imaging.
2025-09-12
Incorporation of SARS-CoV-2 spike NTD to RBD protein vaccine improves immunity against viral variant
By fusing the spike protein's terminal domain (NTD) with its receptor-binding domain (RBD), researchers have engineered a protein vaccine that significantly amplifies both T-cell responses and antibody breadth.
2025-06-25
Can you solve mouse CT imaging with 50um spatial resolution ?
MOLECUBES, a Bruker Company offers small footprint microCT for mice and rats, which meets most of your needs for in-vivo analysis and doesn't sacrifice the budget.
2025-10-22
Refining Biomedical Research Beyond Animal Models
What the Pivot to Human-Based Technologies Means for Science and How 3D Cellular Constructs like Organoids Are Part of the Solution.
2025-10-13
Monitoring mRNA vaccine antigen expression in vivo using PET/CT
The aim of this study was to evaluate the ability of PET/CT imaging to track mRNA vaccine antigen expression in mammalian systems. The researchers used eDHFR as a PET reporter gene, fused to the SARS-CoV-2 spike protein.
2025-09-08
Growing Mature Biofilms for Antimicrobial Screening, Host-pathogen Interactions, and Adhesion
We present the BioFlux shear flow system, a microfluidic flow cell array that enables the growth of biofilms in precisely controlled conditions, including shear stress, temperature, and environmental gas.
2025-06-18
Development of new albumin‑binding radiotracers for PET imaging of CSF
In this study by Peltoniemi et al., PET/CT imaging using the X-CUBE (CT) and ß-CUBE (PET) was used to non-invasively visualize cerebrospinal fluid (CSF) flow and glymphatic system dynamics in rats.
2025-11-28
Measure EV Purity Results by Calculating the Membrane Ratio with the Exoplorer
Working with Extracellular Vesicles (EVs)? Imagine being able to effortlessly measure EV quality. This is possible with the Exoplorer™ Nano-flow Cytometer — a highly effective tool for nanoparticle-level analysis.
2025-10-20
Optimizing Substrate Dosing for ReliableBioluminescence Imaging (BLI)
Bioluminescence imaging relies on precise D-luciferin administration, as dosing variability impacts signal intensity and data consistency. Standardizing substrate delivery is essential for reproducible and high-quality in vivo imaging results.
2025-09-18
Generating High-Quality cDNA Libraries for Efficient Sequencing of T-cell Receptor mRNA
Single-cell omics provide undiluted information about individual cells, such as transcription levels and sequences of highly variable proteins.Miniaturizing the assay helps scale down analysis to the single-cell level without sacrificing data quality
2025-07-02
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Technologies