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High-Throughput UVA-Based Thermal Shift Assays for Hydrophobic Proteins Using the qTOWER iris

This note demonstrates a UVA-based Thermal Shift Assay on the qTOWER iris, enabling sensitive detection of protein stability and expanding qPCR use to protein analysis.

2026-04-23

Application
Scientific paper

PHF19 drives the formation of PRC2 clusters to enhance motility in TNBC cells

Polycomb repressive complex 2 (PRC2) is a key regulator of transcriptional repression and chromatin organization, essential in development and disease. While its enzymatic activity is well characterized, the factors governing PRC2 subnuclear organization, particularly in cancer cells, are largely unknown. Here, the researchers integrate in situ subcellular proteomics, high-resolution imaging, and functional genomics to investigate […]

2026-04-14

Application
Product news
Scientific paper

Accelerating Antibody Discovery with the WOLF G2 Cell Sorter

Site-directed antibodies targeting driver mutations of the KRAS protein

2026-03-16

Application
Scientific paper

Non-invasive real-time pulsed Doppler assessment of blood flow in mouse ophthalmic artery

Imaging was performed under isoflurane anesthesia using the SkyScan 1276 instrument with an X-ray source voltage and current of 70 kV and 200 μA and a 1 mm Aluminum filter. A total of 1200 projection images were acquired at resolution of 13μm.

2026-02-06

Application
Scientific paper

Direct delivery of plasmin using clot-anchoring thrombin-responsive nanoparticles

The targeted fibrinolytic efficacy of the plasmin-loaded CTNPs was then evaluated under flow using the Bioflux microfluidic device.

2026-01-28

Application
Scientific paper

The Path to Clinical Relevance: Moving from Spatial Transcriptomics to Protein Profiling

Spatial biology is a rapidly evolving discipline that advances human health by leveraging imaging technologies. It encompasses research activities ranging from whole-transcriptome profiling to clinically impactful single-protein biomarker tests.

2025-12-02

Application

Standardized Thawing and Sample Preparation of ARCTis Cryopreserved Human Tumor Cells

The standardized and automatic handling of cryopreserved biological samples plays an increasingly important role in today’s in vitro testing. This is due to the trend to develop more complex disease models to increase the data quality of studies.

2026-03-30

Application

Harnessing the WOLF Cell Sorter for Cutting‑Edge Senescence Research

Senescent Endothelial Cells in Cerebral Microcirculation Are Key Drivers of Age-Related Blood–Brain Barrier Disruption, Microvascular Rarefaction, and Neurovascular Coupling Impairment in Mice

2026-02-18

Application
Scientific paper

Metabolomic fingerprints of PAH exposure – identifying toxicological biomarkers in dynamic culture

This study not only highlights the use of spheroids for mechanistic toxicological studies but also provides a framework for identifying potential metabolic biomarkers of PAH exposure. Use of ClinoStar for hepatic HepG2 spheroids made the difference !

2026-02-05

Application
Scientific paper

CXCL12+ fibroblastic reticular cells in lymph nodes facilitate immune tolerance

The popliteal LNs were exposed surgically and confocal intravital imaging was performed (IVM-CMS3). Twenty-five Z-stack images were obtained with a 3 μm axial interval. Time-lapse images were obtained at a 1-minute time interval for 20 minutes.

2026-01-26

Application
Scientific paper

Train yourself on pmod !

Follow up on YouTube series of tutorials about pmod

2025-12-01

Application
Video

Harnessing the Nanoflow cytometer Exoplorer to characterize surface proteins of Exosomes

miR-185-5p Derived From hUC-MSC Exosomes via Suspension Culture Under Hypoxic Conditions Promotes Scarless Wound Healing in Mice by Precisely Regulating Collagen I/III Regeneration

2026-03-19

Application
Scientific paper

Use of Vizgen’s MERSCOPE Platform to Uncover New Insights about Aging

Microglia activation orchestrates CXCL10-mediated CD8+ T cell recruitment to promote aging-related white matter degeneration - peer-reviewed paper outlines aging-related changes in white matter by single-cell and spatial transcriptomics

2026-02-11

Application
Scientific paper

Impact of aging on gene expression response to x-ray irradiation using mouse blood

Mice were restrained in a pie holder without anesthesia and they were either sham-irradiated or exposed to 4Gy x-rays of total body irradiation from an X-RAD 320 Biological Irradiator.

2026-02-02

Application
Scientific paper

Combination of low-energy X-ray & citric acid to inactivate E.coli, S.Typhimurium, L.Monocitogenes

Combined treatment with 0.5 kGy X-ray and 0.1 % CA significantly decreased biofilm cell counts by 5.10, 4.31, and 3.96 log CFU/coupon for E. coli O157:H7, S. Typhimurium, and L. Monocytogenes, respectively.

2025-12-03

Application
Scientific paper