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The Path to Clinical Relevance: Moving from Spatial Transcriptomics to Protein Profiling

Spatial biology is a rapidly evolving discipline that advances human health by leveraging imaging technologies. It encompasses research activities ranging from whole-transcriptome profiling to clinically impactful single-protein biomarker tests.

2025-12-02

Application

Genotype-Specific Macrophage Programs in the NSCLC Microenvironment

Understanding cell-cell interactions within the tumor-immune microenvironment is crucial for advancing cancer therapies. Macrophages show highly variable roles in tumor progression and response, yet the drivers of this complexity remain unclear.

2025-11-26

Scientific paper

Applications: Phase Contrast and Fluorescence Microscopy

Phase contrast and fluorescence microscopy reveals structural and molecular details in cells. Lumascope microscopes are ideally suited for research that requires both, for example this cancer-related study.

2025-08-18

Optimized rare cell isolation for mouse and human samples

This application note introduces the new in situ rinse program. This workflow delivers the same high purity of rare cells as the traditional “serial program” and additionally significantly enhances throughput.

2025-04-29

Application

A comprehensive comparison on clustering methods for multi-slide spatially resolved transcriptomics

This study evaluates clustering methods for multi-slide spatial transcriptomics (ST) data, analyzing preprocessing techniques like PASTE and Harmony to guide method selection.

2025-03-19

Application
Scientific paper

Francisella tularensis induces Th1 like MAIT cells conferring protection against infection

F. tularensis LVS activates MAIT reporter cells in vitro in an MR1-dependent manner and induces a systemic MAIT cell response in vivo.

2025-02-27

Application
Product news
Scientific paper
Technical breakthrough

Gentle Cell Sorting Advancing ALS Research

Researchers using iPSC-derived neurons and glia for ALS models have found that WOLF’s gentle, low-pressure sorting preserves fragile cells’ viability and function—unlike traditional droplet sorters.

2025-10-15

Technical breakthrough

Generating High-Quality cDNA Libraries for Efficient Sequencing of T-cell Receptor mRNA

Single-cell omics provide undiluted information about individual cells, such as transcription levels and sequences of highly variable proteins.Miniaturizing the assay helps scale down analysis to the single-cell level without sacrificing data quality

2025-07-02

Application

Advanced spatial biology sheds new light on therapeutic research

See how high-resolution multiplex immunofluorescence imaging can elucidate the important role the immune system plays in health, disease, and drug development.

2025-04-22

Application
Product news

Breaking Barriers in Spatial Proteomics with Single-Round Imaging

Date & TimeMar 18, 2025 05:00 PM (CET)

2025-03-07

Application
Webinar

Get your cells ready for NGS with tiples nanodispenser MANTIS

Generating high-quality cDNA libraries for efficient sequencing of T-cell receptor mRNA from single cells.

2025-01-06

Application
Scientific paper

Image-activated cell sorting

The NanoCellect VERLO Image-Guided Cell Sorter is mentioned in the attached Nature Reviews Bioengineering paper (Ding et al., 2025) reviewing commercially available Image-Activated Cell Sorting systems.

2025-09-16

Scientific paper

Control of behavioral uncertainty by divergent frontal circuits

Preprint on bioRxiv shows that plasma p-tau181, NfL, and GFAP effectively differentiate Alzheimer’s from FTD and DLB, while Aβ₁₋₄₂/₁₋₄₀ adds little diagnostic value.

2025-06-04

Application
Scientific paper

STAIG: Spatial transcriptomics analysis via image-aided graph contrastive learning

STAIG: Spatial transcriptomics analysis via image-aided graph contrastive learning for domain exploration and alignment-free integration

2025-03-24

Application

VERLO is the Future of Image-Guided Cell Sorting

This presentation introduces the VERLO™ Image-Guided Cell Sorter from NanoCellect. VERLO integrates advanced image-guidance technology with cell sorting, enhancing precision and efficiency.

2025-03-05

Product news
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