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Webinar recording: Development And Optimization Of A 36-Color Panel For Deep Immunophenotyping
In this webinar, Cytek presented the development and optimization of a 36-color full spectrum flow cytometry panel for in-depth immunophenotyping of human T cells, with specific applications in adoptive cell therapy research.
2026-06-19
mRNA vaccine immunity is enhanced by hepatocyte detargeting and not dependent on dendritic cell expression
mRNA vaccine efficacy is enhanced by preventing expression in hepatocytes rather than promoting it in dendritic cells. The findings highlight tissue-specific targeting as a potential strategy for improving vaccines and cancer immunotherapies.
2026-06-05
High-Throughput UVA-Based Thermal Shift Assays for Hydrophobic Proteins Using the qTOWER iris
This note demonstrates a UVA-based Thermal Shift Assay on the qTOWER iris, enabling sensitive detection of protein stability and expanding qPCR use to protein analysis.
2026-04-23
Molecular and Spatial Drivers of Immunotherapy Response in Mucosal Melanoma
Findings suggest that distinct genomic features, tumor states, and microenvironments differentiate ICB response and progression in MM, highlighting key tumor-intrinsic and microenvironmental factors associated with prognosis.
2026-03-18
Use of Vizgen’s MERSCOPE Platform to Uncover New Insights about Aging
Microglia activation orchestrates CXCL10-mediated CD8+ T cell recruitment to promote aging-related white matter degeneration - peer-reviewed paper outlines aging-related changes in white matter by single-cell and spatial transcriptomics
2026-02-11
Gentle Cell Sorting Advancing ALS Research
Researchers using iPSC-derived neurons and glia for ALS models have found that WOLF’s gentle, low-pressure sorting preserves fragile cells’ viability and function—unlike traditional droplet sorters.
2025-10-15
Efficient DNA purification from cells: Automated workflows with sbeadex Lightning and CyBio FeliX
This application note presents a rapid, automated DNA purification workflow using the CyBio FeliX system with sbeadex Lightning technology, enabling high-quality results in just minutes while reducing hands-on time and increasing throughput.
2026-05-06
PHF19 drives the formation of PRC2 clusters to enhance motility in TNBC cells
Polycomb repressive complex 2 (PRC2) is a key regulator of transcriptional repression and chromatin organization, essential in development and disease. While its enzymatic activity is well characterized, the factors governing PRC2 subnuclear organization, particularly in cancer cells, are largely unknown. Here, the researchers integrate in situ subcellular proteomics, high-resolution imaging, and functional genomics to investigate […]
2026-04-14
Combining GrowDex and spheroONE for automated and highly reproducible 3D cell culture workflows
This application note demonstrates the compatibility of spheroONE and GrowDex to automate 3D cell culture workflows. spheroONE is a nanoliter dispenser enabling sorting and isolation of spheroids and organoids.
2026-02-25
The Path to Clinical Relevance: Moving from Spatial Transcriptomics to Protein Profiling
Spatial biology is a rapidly evolving discipline that advances human health by leveraging imaging technologies. It encompasses research activities ranging from whole-transcriptome profiling to clinically impactful single-protein biomarker tests.
2025-12-02
Image-activated cell sorting
The NanoCellect VERLO Image-Guided Cell Sorter is mentioned in the attached Nature Reviews Bioengineering paper (Ding et al., 2025) reviewing commercially available Image-Activated Cell Sorting systems.
2025-09-16
Cutaneous T cell lymphoma atlas reveals malignant TH2 cells supported by a B cell-rich tumor microen
The study provides a high-resolution atlas of cutaneous T cell lymphoma, identifying that malignant cells resemble TH2 cells. It highlights how a B cell-rich microenvironment supports tumor growth, offering new targets for therapy.
2026-05-04
Standardized Thawing and Sample Preparation of ARCTis Cryopreserved Human Tumor Cells
The standardized and automatic handling of cryopreserved biological samples plays an increasingly important role in today’s in vitro testing. This is due to the trend to develop more complex disease models to increase the data quality of studies.
2026-03-30
Integrative multi-omics reveals a regulatory and exhausted T-cell landscape in CLL
T-cell exhaustion contributes to immunotherapy failure in chronic lymphocytic leukemia (CLL). T cells from CLL patients' blood, bone marrow, and lymph nodes were analyzed using single-cell RNA sequencing, mass cytometry, and tissue imaging.
2026-02-12
Genotype-Specific Macrophage Programs in the NSCLC Microenvironment
Understanding cell-cell interactions within the tumor-immune microenvironment is crucial for advancing cancer therapies. Macrophages show highly variable roles in tumor progression and response, yet the drivers of this complexity remain unclear.
2025-11-26
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