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A combination of systemic nanoparticles for caveolae-mediated gene delivery to the brain
This study shows that systemic mannitol induces caveolae in the brain endothelium. Mannitol-modified nanoparticles exploit this to cross the BBB, enhancing gene delivery.
2026-05-20
Quantitative Resolution Enhancement in In Vivo Two-Photon Intravital Imaging
Unlock high-resolution intravital imaging with advanced two-photon microscopy and computational enhancement. Visualize dynamic cellular processes in vivo with clarity, precision, and real-time insight.
2026-05-18
Efficient DNA purification from cells: Automated workflows with sbeadex Lightning and CyBio FeliX
This application note presents a rapid, automated DNA purification workflow using the CyBio FeliX system with sbeadex Lightning technology, enabling high-quality results in just minutes while reducing hands-on time and increasing throughput.
2026-05-06
Introducing Synlight-Pure — Ultra-High Precision Photolabeling for Nanoscopic Proteomic Discovery
The webinar is demonstrating how microscopy-guided, patterned light activation enables protein purification directly from visually defined subcellular structures.
2026-04-22
Comprehensive analysis of B cell repopulation in ocrelizumab-treated patients with MS
Using the Curiox Pluto platform to automate immune profiling, ocrelizumab’s effects in MS reveal repopulation of transitional naïve B cells at 6 months and linked shifts in T/myeloid markers and plasma proteins.
2026-04-07
Microscopy-guided subcellular proteomic discovery by high-speed ultra-content photo-biotinylation
Syncell developed a method combining microscopy, photo-biotinylation, and mass spectrometry, enabling high-resolution mapping of proteins in subcellular regions, accelerating discoveries in spatial proteomics research.
2026-03-23
Combined Denoising and Resolution Enhancement Algorithms for Intravital Two-Photon Imaging
The study compared several image processing techniques, finding that the enhanced Super-Resolution Radial Fluctuations (eSRRF) combined with a trained denoising model significantly improved spatial resolution and mitochondrial structure visualization compared to other algorithms. Algorithms Evaluated: The study tested Gaussian and median filtering against a trained denoising model, followed by resolution enhancement using either eSRRF or […]
2026-05-14
Cutaneous T cell lymphoma atlas reveals malignant TH2 cells supported by a B cell-rich tumor microen
The study provides a high-resolution atlas of cutaneous T cell lymphoma, identifying that malignant cells resemble TH2 cells. It highlights how a B cell-rich microenvironment supports tumor growth, offering new targets for therapy.
2026-05-04
Introducing Orion HT
The New Standard for Spatial Biomarker Development in Translational and Clinical Research
2026-04-20
Webinar recording: Exoplorer – the Nano Flow Cytometer for everyone
Thursday, April 16, 14:00 CET, Riccardo Pasculli, FAS, ACCELA s.r.o.
2026-03-31
Harnessing the Nanoflow cytometer Exoplorer to characterize surface proteins of Exosomes
miR-185-5p Derived From hUC-MSC Exosomes via Suspension Culture Under Hypoxic Conditions Promotes Scarless Wound Healing in Mice by Precisely Regulating Collagen I/III Regeneration
2026-03-19
New product launch: InAlyzer2, Medikors
Next generation DXA Precision Analysis Technology
2026-05-11
High-Throughput UVA-Based Thermal Shift Assays for Hydrophobic Proteins Using the qTOWER iris
This note demonstrates a UVA-based Thermal Shift Assay on the qTOWER iris, enabling sensitive detection of protein stability and expanding qPCR use to protein analysis.
2026-04-23
PHF19 drives the formation of PRC2 clusters to enhance motility in TNBC cells
Polycomb repressive complex 2 (PRC2) is a key regulator of transcriptional repression and chromatin organization, essential in development and disease. While its enzymatic activity is well characterized, the factors governing PRC2 subnuclear organization, particularly in cancer cells, are largely unknown. Here, the researchers integrate in situ subcellular proteomics, high-resolution imaging, and functional genomics to investigate […]
2026-04-14
Standardized Thawing and Sample Preparation of ARCTis Cryopreserved Human Tumor Cells
The standardized and automatic handling of cryopreserved biological samples plays an increasingly important role in today’s in vitro testing. This is due to the trend to develop more complex disease models to increase the data quality of studies.
2026-03-30
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Technologies