Dynamis DNP – Enhancing MRI experiments with unprecedented sensitivity gains

Bruker MRI platforms are ideally suited to utilize the power of the Dynamis in a seamlessly integrated package for groundbreaking translational research.
The Dynamis DNP system enables detection of dilute, natural-abundance metabolites, supporting research in chronic kidney disease (CKD), diabetes, and metabolic disorders. Its rapid polarization and single-scan sensitivity make it ideal for time-sensitive metabolic profiling.
Visualize tumor metabolism and therapeutic response with unprecedented clarity. DNP-enhanced MRI allows for non-invasive mapping of metabolic fluxes in vivo, aiding in the identification of biomarkers and the evaluation of treatment efficacy. Applications include tumor hypoxia, glycolysis, and lactate production studies.
Advance understanding of brain metabolism in health and disease. The Dynamis DNP system supports high-resolution imaging of cerebral metabolic pathways, enabling research into glioma, traumatic brain injury (TBI), and neurodegenerative diseases. Its compatibility with preclinical MRI platforms ensures translational relevance.
Capture dynamic cardiac metabolism in real time. DNP-enhanced MRI enables voxel-by-voxel quantification of metabolic substrates in preclinical models, supporting research into ischemia, heart failure, and cardiomyopathies.

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